2005-2006
Recent
scientific advancements, such as the unraveling of the human
genome and subsequent characterization of specific genetic
changes associated with cancers, are bringing us closer to
discovering more effective preventive agents, improved
diagnostic tools for early detection, and targeted therapies
that are less toxic and more effective.
Despite this
enormous potential, the development of new cancer drugs has
been slow due to the complex biology of individual cancers and
the financial/technical difficulties involved in generating
new agents. Advancements in the areas of chemoprevention and
early detection face even greater challenges and impediments
than many cutting edge treatment options. FOCR believes that
this is due, in large part, to a lack of understanding about
the disease process on the part of the public and lay
government officials in addition to the scientific, medical,
and financial difficulties involved in producing primary and
secondary preventive agents.
Friends of Cancer
Research has initiated an ongoing educational initiative that
will generate awareness in 2005 and 2006 about the substantial
barriers to research advancements in cancer prevention and
early detection, in addition to recommendations for reducing
and eliminating these barriers. The primary vehicle for this
effort to date has been a series of symposia designed to
discuss and develop a suite of priority steps that could
accelerate discoveries in the fields of cancer prevention and
early detection. The first of these meetings was held in
Washington D.C. on July 13th of 2003 and was
co-sponsored by the House Cancer Caucus and the Senate Cancer
Coalition of the U.S. Congress. The second event was held in
Tampa, Florida on February 17th and was conducted
in partnership with the H. Lee Moffitt Cancer Center.
These activities
are designed to educate regulatory and formulary decision
makers, the media, and the public about steps that can be
taken in terms of federal resources, new agency programs, and
policy innovations to result in more efficient translation of
scientific discovery to actual therapies in areas such as
chemoprevention.
For these types of
activities, we typically involve the participation of key
representatives from the U.S. Congress, the National Cancer
Institute, the U.S. Food and Drug Administration, the
pharmaceutical and biotech industries, cancer
patient/survivors, and academia. As an inter-related
component of our scheduled events/activities, FOCR has an
ongoing relationship with experts in cutting edge scientific
fields who help us to insure the credibility and timeliness of
the material covered in our planned activities.
The ultimate goal
if this educational initiative is to generate a powerful set
of ideas for overcoming barriers to cancer prevention and
early detection that can be used by a variety of stakeholders
to generate awareness among key decision makers about the need
for regulatory reforms that make prevention research more
feasible for clinical trial sponsors. A major focus also will
be on how we, as a society, can usher in a new paradigm of
effective diagnostics for early detection.