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FROM BENCH TO BEDSIDE:
DEFEATING
CANCER THROUGH PREVENTION AND EARLY DETECTION |

Full panel
(L-R: Barker, Sporn, Dentzer,
Pearce, Pazdur, and Leaf)

From left to
right: Introductory Speaker Bo Alidge, Guest Speaker Representative Sue Myrick, left side of
panel, right side of panel.
Please click on thumbnail to enlarge
Cure for cancer: nearer
than we thought?
The cure, experts
say, may not lie entirely with treatment but instead with
prevention.
WASHINGTON- In a congressional briefing on Capitol Hill
Tuesday morning July 13th, Friends of Cancer Research, a non-profit
headquartered in the District, hosted a panel discussion by
some of the nation's foremost cancer experts. Focusing on
strategies related to prevention and early detection, the
diverse group of panelists consisted of senior federal and
private sector physicians, administrators, researchers, and
members of the media. Introductory speaker,
Bo Alidge, President of the Cancer Research and Prevention
Foundation set the stage with a call for a paradigm shift in the
public's attitude toward cancer.
The group
repeatedly asserted that rather than counting on 'magic bullet
drugs' to cure established disease, the shortest and most
effective path to the National Cancer Institute's stated goal
of eliminating death and suffering due to cancer by 2015 might
be to avoid the disease in the first place, or to treat it
'presumptively' before it is even diagnosed. Panelist Dr.
Michael Sporn, a 30 year veteran of the war on cancer, and a
pioneer in cancer prevention, said his highest goal in regards
to public education, is to get people to understand that
cancer is not only a disease at the specific point of
diagnosis, it is a chronic process which exists for years
before it is detected. The entire panel supported Dr. Sporn's
message, that significant disease precedes symptoms for years,
and is vastly more curable than advanced disease. Dr. Homer
Pierce, who has devoted decades to the development of cancer
fighting drugs, and is currently a distinguished research
fellow for leading pharmaceutical Eli Lilly and Company
suggested “We must acknowledge that at any give moment,
we all probably have at least a couple of cells in our bodies
that are cancerous, and that rather than responding in fear,
we should be motivated to do what we must to prevent them from
developing into the disease we commonly call cancer.”
Representative Sue Myrick (R-NC), a cancer survivor herself,
was a special guest at the forum, and emphasized the
importance of identifying useful "protein marker" tests as a
tool for early detection. Fortune Magazine editor Clifton
Leaf, also a cancer survivor, seconded Myrick’s call for the
development of biomarkers and other modes of risk assessment
and early detection. Asserting that too many anti-cancer
dollars are devoted to treatment of advanced and often
incurable disease, Leaf suggested they should instead be
focused on preventing or promptly detecting the cancers that
will otherwise strike one out of every two men, and one out of
every three women.
Dr. Anna
Barker, Deputy Director of the National Cancer Institute,
provided details on cutting edge science, such as
nanotechnology and micro-imaging, which will “translate into
cures" through collaboration between the Institute, the FDA,
pharmaceutical companies, and others involved in the effort.
Dr. Rick Pazdur, Director of the FDA’s oncology division,
cautioned that the FDA could not prop up 'shaky science,' no
matter how promising the treatment, citing the Agency's role
in balancing risk against benefit.
Moderated
by Susan Denzter, of the NewsHour with Jim Lehrer, the panel
also debated the value of intellectual property rights, which
provide patent protection, allowing drug companies to
ultimately recoup the enormous costs of new drug discovery,
development, testing, and approval. During an impassioned
response by Mr. Leaf to questions late in the forum, the
tendency of the media to gravitate towards sensation instead
of education was addressed.
Participants
Introductory
Speaker:
Carolyn “Bo”Aldige, President,
Cancer Research and Prevention Foundation
Panelists:
Anna Barker, Ph.D., Deputy Director, NCI
Clifton Leaf, Executive Editor, Fortune Magazine
Rick Pazdur, M.D., Director, FDA’s Oncology Drug Products
Division
Homer Pearce, Ph.D., Cancer Research Fellow, Eli Lilly and
Company
Michael B. Sporn, M.D., Professor of Pharmacology, Dartmouth
Medical School
Moderator:
Susan Dentzer, Health Correspondent, NewsHour with Jim Lehrer
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