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APRIL
2006
> Update on NIH Funding
> Briefing on the Hill: Stopping Cancer Before it Starts
> Dr. von Eschenbach nominated to head FDA
>
FOCR
News
> Science Corner: Critical Path Initiative
> The Changing Face of Scientific Research
>
Spotlight: Dr. William Nelson of Sidney Kimmel Comprehensive Cancer Center
at Johns Hopkins
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FOCR is a non-profit organization that raises awareness and
provides public education on cancer research in order to
accelerate the nation's progress toward better tools for the prevention,
detection, and treatment
of cancer.
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NIH Funding
Update
Zerhouni Testifies and House Fails to Act on
FY 2007 Budget Resolution
NIH Director Elias A. Zerhouni, MD, testified before the House Labor-HHS-Education
Appropriations Subcommittee on Thursday, April 6. Dr. Zerhouni
stressed NIH’s contribution to the nation’s health and economy by
highlighting the return on investment of NIH research and describing
the health benefits that have come from NIH as a result of the
investment in the agency. He pointed out that life expectancy has
increased by six years over the past 30 years. Moreover, he discussed
how NIH estimated the total cumulative investment at the National
Cancer Institute per American over the past 30 years at about $258, or
about $9 per American per year for the entire period.
Before adjourning for a two-week recess, House
Republican leaders decided not to move forward with a plan to bring
the House’s version of a fiscal year (FY) 2007 Budget Resolution to
the floor for a vote... [
click for
full article.]
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Stopping Cancer Before It
Starts, A Hill Briefing for Congressional Staffers

Above: Staffers listen as moderator Susan Dentzer asks panelist Dr.
Sellers how biomarkers will play a role in prevention of cancer.
On April 5 Friends of Cancer Research hosted a
town hall style meeting on cancer prevention and early detection for
congressional staffers entitled “Stopping Cancer Before It Starts:
Issues on Cancer Prevention for Policy Makers.” Conducted in
partnership with the American Association for Cancer Research (AACR),
the event was held in the Rayburn House Office Building and drew over
70 people. The discussion panel featured Anna Barker, Ph.D.
(NCI), Gary Gordon, M.D. Ph.D. (Abbott Labs), Amy Muhlberg, Ph.D.
(Senate HELP committee), Bill Nelson, M.D., Ph.D. (Sidney Kimmel
Cancer Center at Johns Hopkins), Tom Sellers, Ph.D. (H. Lee Moffitt
Cancer Center and Research Institute), and was moderated by Susan
Dentzer of the NewsHour with Jim Lehrer.
[Click for full article.]
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Dr.
Andrew von Eschenbach Nominated to Permanently Head FDA
On
Wednesday, March 15, President Bush nominated Dr. Andrew von Eschenbach
to become permanent Commissioner of the Food and Drug Administration.
Dr. von Eschenbach is currently Acting Commissioner of the FDA after
serving as Director of the National Cancer Institute for over four
years. Dr. von Eschenbach spent much of his academic career at the
highly prestigious M.D. Anderson Cancer Center in Houston as a
nationally recognized urologic surgeon and has contributed more than
200 articles, books, and chapters to the scientific literature. “As
an accomplished physician-investigator and three-time cancer survivor,
Dr. von Eschenbach will bring a proven background of knowledge and
experience on clinical research, clinical practice, and patient care
to the FDA,” Friends Chair Dr. Ellen Sigal said of the announcement.
She continued, “Having worked with Dr. von Eschenbach in his capacity
as Director of the National Cancer Institute, I am confident that he
will continue to make sound scientifically-based decisions that will
benefit the entire research continuum — from the discovery of new
knowledge about the process of disease to the delivery of new, more
effective, and safer treatments.” (Picture from
www.cancer.gov)
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The Changing Face of Scientific
Research
A recent article by Steve Lohr (NY Times
4/10/06 U.S. Research Funds Often Lead to Start-Ups. Study Says)
describes a changing face of scientific research. A new study,
performed by economists from Indiana University and the Max Plank
Institute of Economics, shows increasing involvement of academic
researchers in the commercial marketplace. The majority of university
scientists still pursue patent rights on their ideas and inventions
through the traditional method of using the institution’s technology
transfer office. However, the study shows that 30 percent of National
Cancer Institute grant supported scientists who received patents from
1998-2002 did so independent of their university. Furthermore, one
quarter of these scientists turned entrepreneurs had started their own
business to commercialize their products. This study provides an
interesting aspect of how federal grants lead to product research and
development that ultimately has a larger than expected impact on the
economy.
For more information:
Link to NY Times article:
http://www.nytimes.com/2006/04/10/business/10cancer.html?_r=1&oref=slogin
Link to study:
http://www.kauffman.org/pdf/scientist_entrepreneurs_audretsch.pdf
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FRIENDS' NEWS
FOCR Board Members
Featured in "Extraordinary Women" Book
Friends
of Cancer Research Chair, Ellen Sigal, and Board Member, Debbie
Dingell, were featured in a recently published book titled,
“Extraordinary Women: Fantasies Revealed.” The book profiles 58
nationally renowned female figures such as former Secretary of State
Madeline Albright, journalist Ann Curry, feminist Betty Friedan, and
writer Cokie Roberts. The women’s profiles, however, are not of the
roles they are publicly known for today, but rather the role they
envisioned themselves as children. After being asked their
childhood fantasy, each woman was photographed in the role – making
for an entertaining collection of imaginative pictures where we see
Madeline Albright as a chess champion, Joan Rivers as an archeologist,
and Olympic gymnast Dominique Dawes as a Supreme Court Justice. The
juxtaposition of each woman’s childhood aspirations versus their adult
accomplishments sets the stage for an insightful and inspirational
patchwork of personal narratives demonstrating that “Sometimes a
detour leads to an open road.” The book was the vision of two
fellow ‘extraordinary’ Washingtonians; Ilene Leventhal and Francine
Levinson, who each founded their own non-profit to help D.C.’s less
fortunate. Proceeds from the sale of the book will benefit their
respective organizations; Hand to Hand Eviction Prevention Program and
the Metropolitan Police Boys and Girls Clubs of Greater Washington,
D.C. (Picture from Barnes and Noble's website.)
The book is available
to purchase online at:
Barnes and Nobles.com
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Back to the Future
Friends of Cancer
Research is excited to announce it’s selection as a charity recipient
of Earthcapsule.com, a website launched in March that provides
visitors around the world with an innovative and inexpensive way to
preserve their personal messages for future generations to come. The
website takes a digital approach to the age-old idea of time capsules
using HD-Rom technology and a network of trustees around the world
charged with protecting the capsules, which will be deposited around
the globe, for fifty years. Earth Capsule’s Charity Network was
created to further their mission of preserving culture for tomorrow
while helping the citizens of today. For more information on
EarthCapsule, please visit:
www.earthcapsule.com
Friends Responds to
Letters from 7th Grade Class
The
staff at Friends of Cancer Research was both surprised and touched
this past month to receive letters from a seventh grade class in
Madison, Tennessee voicing their support for our mission of advancing
cancer research. Written in response to a class assignment titled
“Project Empathy” in connection to reading The Diary of Anne Frank,
the letters discussed the importance of not standing idle while others
are suffering. While many of the students shared their personal
connections to cancer, all professed their desire to get involved so
that they and others would not have to face cancer in the future.
Friends of Cancer Research wrote the class a detailed response
explaining how cancer is formed, found, and treated, as well as ways
the students themselves could help make their future cancer free. (Picture
from The Ann Frank Center's website.)
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Science Corner – April 2006
The C-Path Institute:
Trailblazing the Critical Path
On March 16, 2006, the
Federal Drug Administration (FDA) revealed many of the details
surrounding its Critical Path Initiative. The Initiative was created
to ensure that discoveries made at the basic science level
successfully translate into new treatments and tools readily available
to the public. Six topic areas were identified as the focal
opportunities to improve new medical product development including:
biomarker development, streamlining of clinical trials, utilizing
bioinformatics, updating manufacturing practices, addressing urgent
health concerns, and attention to pediatrics. By further developing
each of the six target areas, the FDA hopes to revolutionize the
medical product development process.
[click for full article]
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Dr. William Nelson
of the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Dr.
William G. Nelson is Associate Director of Translational Research at
The Sidney Kimmel Cancer Center at Johns Hopkins. He is also a
Professor of Oncology, Urology, Pharmacology, Medicine, Pathology and
holds a joint appointment in Environmental Health Sciences at The
Johns Hopkins Bloomberg School of Public Health. Dr. Nelson is board
certified in medical oncology and internal medicine. He received both
his M.D. and Ph.D. in pharmacology from The Johns Hopkins University
School of Medicine. His research is focused on the early stages of
prostate cancer development, specifically methylation changes present
in prostate cancer and precursor cells. Detecting such changes may
serve as a biomarker useful in the advancement of prostate cancer
treatment and prevention.
[Read
this month's In The Spotlight]
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