JANUARY 2005

Hightlights of 2004 including
> FOCR President and Chair named "Washingtonians of the Year"
> Dr. Lester Crawford of the FDA and Dr. Mark McClellan among honorees of the Cancer Leadership Awards Dinner

> EIF Biomarker Discovery Project


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FOCR is a non-profit organization that raises awareness and provides public education on cancer research in order to accelerate the nation's progress toward prevention and treatment of cancer.

 

Special Edition
2004 Highlights: The Year in Review

Welcome to the special "Year in Review" edition of the Friends of Cancer Research Newsletter. We would like to thank all of you who helped shape our organization’s success by dedicating your time and resources to the shared vision of accelerating the nation’s progress toward prevention and treatment of cancer. The cancer community shared some great victories in 2004 in addition to some disappointments. Given the federal budget constraints and the intense focus on national security, 2005 also is going to be a very challenging year for cancer research funding and other cancer policy priorities. However, we can yield some important breakthroughs both politically and scientifically in the months ahead if we all work together on behalf of the millions of Americans who will be affected by the disease in the years ahead and are counting on us to continue working to accelerate advancements in cancer research.

Ellen V. Sigal, Ph.D., ChairMarlene A. Malek, RN, President, and Alan Balch, Ph.D., Director

FOCR President and Chair named "Washingtonian's of the Year" by Washingtonian Magazine

Friends of Cancer Research President, Marlene Malek, and Chairperson , Ellen Sigal, were honored with the Washingtonian Magazine's "2004 Washingtonians of the Year" Award in the January 2005 issue. "For 33 years, the Washingtonian ("the magazine that Washington lives by") has honored people who make Washington a better place.  And each year, those who make a difference inspire others to make this a better city."  says the Washingtonian.com.  As described on page 53,  Sigal and Malek were honored for their exemplary contributions to the cancer community.  Authors Leslie Milk and Ellen Ryan write, "The two dynamos have been matchmakers for public-private partnerships to fund research and clinical trials.  They have organized policy forums to bring together researchers, federal health agencies, patients, Congress, and industry leaders to develop a strategy on funding research and fighting cancer."  The article includes a special tribute from Dr. Andrew von Eschenbach, Director of the National Cancer Institute:  "The impact they have had on improving the lives of cancer patients is multiplied by their influence in the cancer research and advocacy community.  The quantity and quality of life for cancer patients is increasing, and they are at the center of the formula for success." (Article posted with special permission from the Washingtonian Magazine, picture courtesy of Gary Landsman, photographer) Click on link here to read full article. (Caution: File is large and may take time to fully upload to screen.)

Dartmouth Town Hall

On March 5th, Friends of Cancer Research, in partnership with Research!America and Dartmouth College, convened a town hall event entitled: “Transforming Medicine: Accelerating the Impact of Scientific Discovery on Patient Care.” Held at Dartmouth’s Norris Cotton Cancer Center, the event featured keynote addresses from Senator Judd Gregg (R-NH), NIH Director Elias Zerhouni, and NCI Director Andrew von Eschenbach.

Left: Senator Judd Gregg at the FOCR/Dartmouth town hall.

The interactive forum explored the impact of scientific discovery on patient care, reviewed the NIH Roadmap, and discussed options for accelerating scientific discovery.  The ensuing panel discussion was moderated by Susan Dentzer (Head of the Health Policy Unit for the NewsHour with Jim Lehrer) and included Dr. Mark A. Israel (Director of the Norris Cancer Center), Dr. Peter Corr (Sr. VP of Science and Technology for Pfizer), Dr. Allen J. Dietrich (Norris Cotton Cancer Center), Dr. Nancy A. Speck (Norris Cotton Cancer Center), and cancer survivor Nancy Hellman (Smith College, Picker Engineering Program). 

 Capitol Hill Symposium

Friends of Cancer Research, in conjunction with the House Cancer Caucus and the Senate Cancer Coalition, hosted a panel discussion on July 13th dealing with cancer prevention and early detection.   The event enabled some of the nation’s foremost cancer experts to explore the opportunities and barriers for translating recent discoveries in the human genome into cutting edge medical advancements for the prevention and early detection of cancer. 


Above: Representative Sue Myrick (R-NC, 9th) speaks to the July 2004 FOCR event on Capitol Hill.

The keynote address was provided by Representative Sue Myrick (R-NC, 9th), a cancer survivor and co-chair of the House Cancer Caucus.  Carolyn “Bo” Aldige, President of the Cancer Research and Prevention Foundation and a Friends’ Board Member, provided introductory remarks.  The panel discussion was moderated by Susan Dentzer, Health Correspondent for the NewsHour with Jim Lehrer on PBS.  Panelists included Anna Barker, Ph.D. (Deputy Director, NCI), Clifton Leaf (Executive Editor, Fortune Magazine), Dr. Richard Pazdur (Director, Oncology Drug Products Division, FDA), Dr. Homer Pearce (Distinguished Cancer Research Fellow, Eli Lilly and Company), Dr. Michael B. Sporn (Professor of Pharmacology, Dartmouth Medical School).  Following the event, Clifton Leaf answered audience questions about his March 2004 Fortune Magazine cover story entitled “Why We’re Losing the War on Cancer (and How to Win it).”

 Cancer Leadership Awards Dinner

Friends of Cancer Research President, Marlene Malek, and Chairperson, Ellen Sigal, hosted an Awards Dinner at the Malek residence on the evening of September 29th.  Stressing the importance of collaboration and cooperation  between advocacy groups, government, and the private sector, the  event  honored innovative leaders from both the government and corporate arenas for their outstanding contributions to the fight against cancer.   A willingness to actively and directly engage the cancer community on issues of great significance to cancer patients, researchers, and physicians was a characteristic common to all the award winners.

Honorees included Dr. Lester Crawford, Acting Commissioner of the Food and Drug Administration, Dr. Andrew C. von Eschenbach,  Director of the National Cancer Institute,  Clifton Leaf, Executive Editor of Fortune Magazine, and Dr. Mark McClellan, Administrator of the Centers for Medicare and Medicaid Services.  Dr. Anna Barker of the NCI and Dr. Janet Woodcock of the FDA also received special recognition for their leadership on the NCI/FDA Oncology Task Force, which allows the two agencies to share knowledge and resources in a manner that facilitates the development of new cancer drugs and speeds their delivery to patients.


 

Above, from left or right: Dr. Ellen Sigal (FOCR), Dr. Lester Crawford (FDA), Dr. Anna Barker (NCI), Clifton Leaf (Fortune Magazine), Marlene Malek (FOCR), Dr. Andrew von Eschenbach (NCI), and Dr. Janet Woodcock (FDA).


Left, from left to right: Dr. Ellen Sigal, Dr. Mark McClellan (CMS), and Marlene Malek.

 

Biomarker Discovery Project

Throughout 2004, Friends’ Chairperson Ellen Sigal assisted the Entertainment Industry Foundation (EIF) with the formation of a multi-disciplinary project comprised of world-renowned scientists from multiple institutions to identify and develop effective technologies for molecular diagnostics.  This collective endeavor, entitled the “Biomarker Discovery Project,” is part of a new program operated by the EIF’s Women’s Cancer Research Fund. 

This fund will provide millions of charitable dollars to support innovative research, education and outreach directed at developing more effective approaches to the early diagnosis, treatment and prevention of all women’s cancers. The project was officially launched at a March 1st Hollywood gala sponsored by Saks Fifth Avenue and chaired by Rita Wilson, Tom Hanks, Kate Capshaw, and Steven Spielberg.  Thanks to a grant from the Entertainment Industry Foundation, Friends of Cancer Research provided educational, strategic, and technical support to this remarkable and noteworthy endeavor in 2004 and will continue to do so in 2005.


Above: Officers, scientists, and advisors for the Biomarker Discovery Project among those pictured include EIF President and CEO Lisa Paulsen, members of the Biomarker Discovery Project Oversight Committee (Dr. Rick Klausner, Dr. David Baltimore, Dr. Ellen Sigal, Dr. Larry Platt, Dr. Phillip Sharp, and Dr. J. Michael Bishop), and members of the Women's Cancer Research Fund Marion Laurie, Kelly Meyer, Quinn Ezralow, and Jamie Tisch.


Left: Friends of Cancer Research Board Member and CEO of Paramount Pictures Sherry Lansing with Friends of Cancer Research Chair Ellen Sigal at the celebrity studded March 2004 Entertainment Industry Hollywood Gala benefiting the Women's Cancer Research Fund.

 

FDA Initiative

In an effort to help get safer and more effective oncology products to patients sooner, Friends of Cancer Research invested an enormous amount of effort in 2004 working alongside and in concert with top cancer research scientists, advocacy leaders and professional society directors to generate ideas and momentum for improving the FDA’s review process. On July 16th, HHS Secretary Tommy Thompson announced plans to consolidate aspects of the FDA’s oncology activities by creating a new Office of Oncology Drug Products with control over an array of biologics, drugs and imaging technologies.  As a subset of the office, the FDA will create an “Oncology Program” designed to better coordinate and integrate cancer-related activities throughout the agency.  In the wake of these announcements, Friends has played an active role in promoting a forum for discussion and ideas about these important changes.

 Clinical Trials

 "Overcoming Barriers to Early Phase Clinical Trials" Semi Annual Workshops

In 2004, Friends of Cancer Research participated in two workshops hosted by the Association of American Cancer Institutes (AACI) for grant recipients of a two-year, $5.7 million research initiative made possible through collaboration between the NCI, the FNIH (Foundation for the National Institutes of Health), AACI, and Friends of Cancer Research along with five industry partners: Aventis, Bristol-Myers Squibb, Eli Lilly, GlaxoSmithKline, and Novartis.

As a result of this public-private partnership entitled “Overcoming Barriers to Early Phase Clinical Trials,” six academic institutions were awarded research grants to explore strategies for improving clinical trial accrual, particularly among minority and geriatric populations.  These semi-annual workshops allow scientists from the six grantee institutions an opportunity to share ideas and update project partners about their progress.

On Capitol Hill

Increasing Awarness and Support of Cancer Research among Congress

Friends of Cancer Research continued to work with Congress to increase awareness and support of cancer research. We are pleased that the following language was included in the Congressional Record as part of the conference report and statement (H. REPT. 108–792) on the Consolidated Appropriations Act, 2005 (H.R. 4818) – the omnibus appropriations package that included the 2005 funding levels for the National Institutes of Health. 

“The conferees support the efforts of HHS to provide for a stronger and more consistent approach to the review process for drug and most therapeutic biologics used to diagnose, treat, and prevent cancer.

Unprecedented progress in fields such as nanotechnology, proteomics, and genomics hold the promise of vast improvements in our ability to prevent cancer, diagnose it at earlier stage, and treat it more effectively through targeted therapies. The conferees encourage and support the efforts of the HHS agencies, including NCI and FDA, to keep pace with scientific discovery in these areas, particularly as they apply to  prevention.”

Vol. 150 FRIDAY, NOVEMBER 19, 2004 No. 134—Book II, page H10668.


Friends of Cancer Research
wishes you a happy and healthy 2005!

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